Bupropion and nicotine patch as smoking cessation aids in alcoholics

This is a double-blind placebo-controlled study of sustained-release bupropion as a smoking cessation aid in alcoholics undergoing treatment for their alcoholism.

Participants (N=58) were enrolled within 1 week of entry into alcohol treatment from community and Veterans Affairs Substance Use Disorder programs.

All participants received nicotine patch and were invited to attend a smoking cessation lecture and group. Cigarette smoking and alcohol outcomes were measured at 6 months.

Bupropion when added to nicotine patch did not improve smoking outcomes.

One third of participants on bupropion reported discontinuing the drug during weeks 1-4.

Participants reported cigarette outcomes with nicotine patch that are similar to those seen in the general population.

All study participants significantly reduced cigarette use.

Comorbid affective disorder or antipersonality disorder did not affect outcomes.

Alcohol outcomes were improved in those who discontinued cigarettes.

Research; Grant KM, Kelley SS, Smith LM, Agrawal S, Meyer JR, Romberger DJ. Bupropion and nicotine patch as smoking cessation aids in alcoholics Alcohol. 2007 Aug;41(5):381-391.
The Easy Way to Stop Smoking: Join the Millions Who Have Become Nonsmokers Using the Easyway Method
by Allen Carr

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Understanding the High-Functioning Alcoholic: Professional Views and Personal Insights (The Praeger Series on Contemporary Health and Living)
Alcoholics Anonymous: Big Book, First Edition
Alcoholics Anonymous: The Story of How Many Thousands of Men and Women Have Recovered from Alcoholism
The Complete ACOA Sourcebook: Adult Children of Alcoholics at Home, at Work and in Love


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